Considering CBD Oil with Zoloft? Here’s What You Should Know

By | 12 June 2023
Considering CBD Oil with Zoloft? Here’s What You Should Know Considering CBD Oil with Zoloft? Here's What You Should Know


Considering CBD Oil with Zoloft? Here’s What You Should Know

So you're on Zoloft and considering trying CBD oil? You're not alone. CBD has become increasingly popular for various reasons, and are wondering if it's safe to use while taking prescription medications like Zoloft. In this article, we'll discuss everything you need to know before adding CBD oil to your .

What is CBD Oil?

CBD oil is made from the flowers and leaves of the . It contains cannabidiol, a non-psychoactive compound that with receptors in the 's endocannabinoid system to produce various effects. Unlike THC, CBD won't make you high or impair your judgment.

What is Zoloft?

Zoloft is a selective serotonin reuptake inhibitor (SSRI) used to depression and disorders. It works by increasing levels of serotonin, a neurotransmitter that regulates , sleep, , and other functions.

Can You Take CBD Oil with Zoloft?

There isn't enough research to determine whether CBD oil is safe to take with Zoloft or other SSRIs. Some studies suggest that CBD may enhance the effects of antidepressants, while others indicate that it may interfere with their metabolism and the of side effects.

What are the Risks of Combining CBD Oil and Zoloft?

The risks of combining CBD oil and Zoloft include:

  • Serotonin syndrome: CBD oil and Zoloft both increase serotonin levels, and combining them may lead to a potentially life-threatening condition called serotonin syndrome. Symptoms may include agitation, confusion, hallucinations, fast heartbeat, high blood pressure, muscle rigidity, and fever.
  • Liver damage: Both CBD and Zoloft are metabolized in the liver, and taking both may increase the risk of liver damage or .
  • Blood thinning: CBD oil may interact with blood-thinning medications like warfarin and increase the risk of bleeding.
  • Sedation: CBD oil may cause drowsiness or sedation, and taking it with Zoloft may enhance this effect.

What are the of Combining CBD Oil and Zoloft?

There isn't enough research to determine the benefits of combining CBD oil and Zoloft. However, some anecdotal reports suggest that CBD oil may enhance the effects of Zoloft and reduce anxiety and depression symptoms.

What Should You Do if You Want to Try CBD Oil with Zoloft?

If you're considering adding CBD oil to your Zoloft regimen, here's what you should do:

  • Consult your doctor: Talk to your doctor or psychiatrist before taking any new supplement or medication. They can advise you on the potential risks and benefits of combining CBD oil and Zoloft based on your individual health and medication history.
  • with a low dose: If your doctor approves the use of CBD oil, start with a low dose and gradually increase it until you the desired effect. Don't exceed the .
  • Monitor your symptoms: track of your mood, sleep, and other symptoms while taking CBD oil with Zoloft. If you experience any adverse effects or no improvement in your symptoms, stop taking CBD oil and consult your doctor.
  • Choose a reputable brand: Look for CBD oil that's been third-party tested for purity and . Avoid products that contain additives or contaminants.


  • Is CBD oil legal?
  • It depends on your location. In the United States, CBD oil derived from hemp is legal under the 2018 Farm Bill if it contains less than 0.3% THC. However, some states may have additional restrictions or require a medical prescription.

  • What are the side effects of CBD oil?
  • The side effects of CBD oil may include dry mouth, drowsiness, fatigue, nausea, diarrhea, changes in appetite, and . These are usually mild and temporary, but some people may experience more severe reactions.

  • How long do the effects of CBD oil last?
  • The effects of CBD oil may last between 2-6 hours, depending on the dosage, method of administration, and individual metabolism. However, the duration may be shorter or longer in some cases.

  • Can you overdose on CBD oil?
  • It's unlikely to overdose on CBD oil, as it's non-toxic and non-addictive. However, taking may increase the risk of side effects or interactions with other medications or supplements.

  • Can CBD oil cause a false-positive drug test?
  • CBD oil may contain small amounts of THC, which can accumulate in the body over time and trigger a positive drug test. However, the amount of THC is usually too low to cause intoxication or impair your cognitive function.

In conclusion, combining CBD oil with Zoloft may carry some risks and benefits. It's crucial to consult your doctor before trying any new supplement or medication and monitor your symptoms closely. By following these , you can make an informed decision about oil with Zoloft and your mental health and well-being.